AlphaGenome maps 9B DNA variants (spectrum.ieee.org)

73 pointsby ltononro3 days ago6 comments

epistasis 6 hours ago

Prior post: https://news.ycombinator.com/item?id=49611251

tusimi 7 hours ago

google PR machine on relatively low-impact science goin pretty hard

ltononro 6 hours ago

Do you really think that tho? I mean, it is the only one doing something other than all-in LLM BenchMaxxing lmao :D

mbreese 3 hours ago

This current project is effectively a cache database for an earlier tool. The earlier project is where the main impact is - predicting the functional effect of a variant in the human genome.

For this updated project, they effectively ran the earlier tool for all possible variants in the genome (3 billion bases in the genome * 3 single nucleotide variants = 9 billion). It’s a very useful project for people like me, but the major advance was already done (admittedly by the DeepMind team).

samuell 6 hours ago

Now do the combinations of them.

ltononro 6 hours ago

boom